Thursday, May 7, 2015

Treatment and progression of AML

Like many kinds of cancers, the prognosis and treatment options for acute myeloid leukemia depend on many different factors. Including the AML subtype, treatment response, and risk stratification. There are also different factors like your white blood cell count, your age, and your overall health that will have an impact on which treatment option may be the right one for you.

Since there are so many different combinations of contributing factors to one specific patient, we will discuss the two main types of treatment for AML: Chemotherapy, and Bone Marrow Transplants.

Chemotherapy

There are a number of chemotherapy regimens that have shown to be effective against AML. The goal of chemotherapy treatment is to kill the malignant cells without damaging the residual bone marrow cells. 

Clinical studies are constantly underway to discover the best regimens, doses, and treatment schedules for AML.



Bone Marrow Transplants

There are three different kinds of bone marrow transplants:

Allogeneic bone marrow transplants use stem cells from a donor, and are the most common type of transplants used for this disease. Most of the time, the donor’s genes must match some of your own, and be a good “match” for you. This kind of donor can be related, by blood, or unrelated, from a stranger whose genes match yours enough to be fit for a transplant.




            
Umbilical cord blood transplant is a type of allogeneic transplant, where cells are removed from a newborn baby’s umbilical cord, and are then frozen and stored for a recipient who needs it.


Autologous bone marrow transplants use stem cells that were removed from your own body, before receiving high-dose chemotherapy or radiation treatment. Your own stem cells are stored in a freezer and kept aside, this is called cryopreservation.







http://www.seattlecca.org/diseases/adult-acute-myeloid-leukemia-treatment.cfm

http://www.nlm.nih.gov/medlineplus/ency/article/003009.htm

3 comments:

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